Brain alterations in autism
Brain mechanisms of autism spectrum disorder, including white matter integrity and temporal lobe volume.
Research
My work centers on how brain regions interact, measured mainly with fMRI, and how those interactions change across tasks, development and disorders.
Themes
Connectivity during movie watching
Measuring dynamic and stationary connectivity during naturalistic viewing, from childhood to early adulthood.
Connectivity across task conditions
How connectivity and network organization shift between rest, tasks and movies, using PPI, beta series, sliding window and intersubject correlation.
Modulation by other regions
How a third region changes the connectivity between two others, in resting-state and task data.
Metabolic & molecular connectivity
Metabolic connectivity from FDG-PET, including effects of aging. I chair the Outreach Council of the Molecular Connectivity Working Group.
Collaborators
- Dr. Bharat Biswal, NJIT
- Dr. Mengjia Xu, NJIT
- Dr. Zhiguo Zhang, HIT
- Dr. Ting Xu, Child Mind Institute
Research support
- Current
NJ ACTS (NJ Alliance for Clinical and Translational Science): Establishing a Standardized Data Access Protocol (SDAP) to Resolve Data Fragmentation in the US Molecular Imaging Ecosystem (PI)2026–2027 - Current
NJDOH: Eye-movement patterns and brain activity in autism spectrum disorder through deep learning-based eye-tracking with fMRI (PI)2024–2026 - Completed
NIH R15: Functional brain developments during movie watching and resting-state in autism spectrum disorder (PI)2021–2025 - Completed
NJDOH: Sex differences in children with autism using multimodal neuroimaging (PI)2016–2018